![]() ![]() Conversely, there is evidence that some antidepressants may be useful in the treatment of sleep disorders such as night terrors. Patients with other sleep disorders such as restless legs syndrome and REM sleep behaviour disorder should be identified before choosing a treatment, as some antidepressants worsen these conditions. In these patients, the choice of a safely used and effective antidepressant which improves sleep in short term is indicated. But up to one in five Americans have difficulty getting back to sleepa frustrating, sleep-robbing problem that experts call sleep maintenance insomnia. When it comes to observable wake-ups, most people have about two or three per night. Sleep improvement earlier in treatment may be an important clinical goal in some patients, perhaps when insomnia is particularly distressing, or to ensure compliance. Most of us experience mini-awakenings without even noticing themup to 20 times per hour. In general, the objectively measured sleep of depressed patients improves during 3-4 weeks of effective antidepressant treatment with most agents, as does their subjective impression of their sleep. However, these effects are fairly short-lived and there are very few significant differences between drugs after a few weeks of treatment. Some antidepressants such as clomipramine and the selective serotonin receptor inhibitors (SSRIs), particularly fluoxetine, are sleep-disturbing early in treatment and some others such as amitriptyline and the newer serotonin 5-HT2-receptor antagonists are sleep promoting. Sleep initiation and maintenance are also affected by antidepressants, but the effects are much less consistent between drugs. The decrease in amount of REM sleep appears to be greatest early in treatment, and gradually diminishes during long-term treatment, except after monoamine oxidase inhibitors when REM sleep is often absent for many months. Prazosin 2mg to reduce intense nightmares (the wake up at 2am every night, screaming bloody murder, leaving you shaking like a leaf for 30 minutes kind of nightmares) Melatonin 3mg. Antidepressants that increase serotonin function by blocking reuptake or by inhibiting metabolism have the greatest effect on REM sleep. Clonidine 0.2mg (anti-hypertensive) to help me relax before bed. Reductions in the amount of REM sleep and increases in REM sleep onset latency are seen after taking antidepressants, both in healthy volunteers and in depressed patients. Your doctor can prescribe the appropriate medication for your particular sleep problems. See the articles below for more information regarding this. In fact, diets high in lauric acid are positively associated with long, uninterrupted sleep. These effects are greatest and most consistent on rapid eye movement (REM) sleep, and tend to be in the opposite direction to the sleep abnormalities found in major depression, but are usually of greater degree. Listed below are some of the types of drugs used to treat sleep disorders. I did some further research and found out that lauric acid aka dodecanoic acid aka C:12 (found almost exclusively in coconuts) is strongly associated with sleep maintenance. Most antidepressants change sleep in particular, they alter the physiological patterns of sleep stages recorded overnight with EEG and other physiological measures.
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